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PULMONARY Disease With EOSINOPHILIA due to Drug sensitivity

It appears in x-ray as Patchy nonsegmental, peripheral parenchymal consolidation with blood eosinophilia.

Some known drugs like Sulfonamides, penicillin, isoniazid, and many other medications. Nitrofurantoin causes a diffuse reticular pattern. Withdrawal of the drug results in prompt disappearance of the clinical and radiographic manifestations.

Nitrofurantoin-induced lung disease. Mixed alveolar and interstitial pattern in an elderly woman who presented with progressive cough and dyspnea after the long-term use of nitrofurantoin for recurring urinary tract infections.

Methotrexate-induced lung disease. The diffuse, bilateral, patchy densities were changeable and fleeting during the illness. The radiographic findings cleared completely after steroid therapy.